PRKDC anticorps (C-Term)

N° du produit ABIN7451558

L’anticorps Lapin Polyclonal anti-PRKDC a été validé pour WB et IP. Il convient pour détecter PRKDC dans des échantillons de Humain.

Aperçu rapide pour PRKDC anticorps (C-Term) (ABIN7451558)

Antigène: PRKDC (Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PRKDC est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Détail du produit anti-PRKDC anticorps

Épitope: C-Term

Fonction: Rabbit anti-DNA-PKcs Antibody, Affinity Purified

Homologie: Mouse

Purification: Affinity Purified

Immunogène: between AA 4075 and C-term

Isotype: IgG

Information d'application

Indications d'application:

IP: 2 - 5 μg/mg lysate. Ku-80 co-immunoprecipitates with DNA-PKcs when using BL2406.

WB: 1:1,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur PRKDC

Antigène: PRKDC (Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC))

Autre désignation: DNA-PKcs

Sujet: Background: DNA-PKcs is the catalytic subunit of a DNA-dependent serine-threonine protein kinase (DNA-PK). DNA-PK is a heterotrimer comprised of DNA-PKcs and the Ku709/Ku86 dimer. DNA-PK is involved in DNA damage repair and V(D)J recombination. DNA-PK phosphorylates Artemis, a protein required for nonhomologous end-joining and is necessary for the loading of Artemis on damaged DNA.

ID gène: 5591

NCBI Accession: NP_008835

UniProt: P78527

Pathways: Réparation de l'ADN, Production of Molecular Mediator of Immune Response